Pentobarbital will lower the level or influence of tinidazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. pentobarbital will lower the extent or impact of tamoxifen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Abrupt withdrawal of antiseizure medicines might raise seizure frequency, withdraw pentobarbital step by ste... https://donaldc963klm2.wikicarrier.com/user