Epidural clonidine applied as an adjunct to nearby anesthetics has three distinct mechanisms of action. Initial, the stimulation of alpha-two-receptors within the dorsal horn minimizes discomfort transmission. Secondly, clonidine may cause nearby vasoconstriction that limits vascular removal of local epidural anesthetics. Clonidine treats high blood pressure level by stimulating https://www.proleviate.com/post/the-new-pain-killer-conolidine